Analytical Data
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Gene name
SLC2A9
- Application
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Alternative Names
SLC2A9；GLUT9；Solute carrier family 2. facilitated glucose transporter member 9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NRM0
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Expression Region
1-540aa
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AA Sequence
MARKQNRNSKELGLVPLTDDTSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEKIDSAVTDGKINGRP
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Molecular Weight
60.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC2A9, a member of the solute carrier family of transporters, specifically encodes the glucose transporter 9 (GLUT9), which plays a crucial role in the renal reabsorption of urate and glucose transport. The protein's function is particularly significant in the context of gout and hyperuricemia, conditions characterized by elevated serum urate levels. Genetic studies have identified several polymorphisms within the SLC2A9 gene that are associated with urate levels and the risk of developing gout. Furthermore, SLC2A9 has been implicated in the regulation of glucose homeostasis, suggesting its potential as a target for metabolic disorder treatments. Research on recombinant SLC2A9 protein has enabled a deeper understanding of its structural and functional properties, facilitating the elucidation of its transport mechanisms. Additionally, studies utilizing this recombinant protein have provided insights into its interaction with various metabolites and pharmacological agents, thus paving the way for novel therapeutic strategies in managing conditions related to dysregulated urate and glucose levels. The ongoing investigation into SLC2A9 is poised to enhance our understanding of its physiological significance and therapeutic potential in metabolic and renal disorders.
