Cat: PA2000-4974

Recombinant Human GLP2R Protein,His

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Analytical Data

  • Gene name

    GLP2R

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    GLP2R;Glucagon-like peptide 2 receptor

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    GLP2R

  • Expression Region

    1-553aa

  • AA Sequence

    MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI

  • Molecular Weight

    64.0 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

Glucagon-like peptide-2 receptor (GLP2R) is a member of the glucagon receptor family, primarily involved in regulating intestinal growth and function. It is activated by glucagon-like peptide-2 (GLP-2), a gut-derived hormone that plays a crucial role in enhancing intestinal absorption, promoting mucosal growth, and reducing apoptosis of intestinal epithelial cells. Research into GLP2R has gained significant attention due to its potential therapeutic applications in gastrointestinal diseases, such as inflammatory bowel disease, short bowel syndrome, and other disorders characterized by intestinal malabsorption. Recombinant GLP2R proteins are essential tools for studying the structural and functional properties of this receptor, facilitating a deeper understanding of its signaling pathways and interactions with ligands. These studies may lead to the development of novel therapeutics aimed at modulating GLP2R activity, thereby improving intestinal health and function. The advancement of recombinant protein technologies has enabled researchers to produce high-quality GLP2R proteins for in vitro and in vivo studies, paving the way for innovative approaches in gastrointestinal medicine.

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