Cat: PA2000-4955

Recombinant Human PLA2G2E Protein,His

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Analytical Data

  • 基因名

    PLA2G2E

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    gE;Group IIE secretory phospholipase A2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9NZK7

  • 表达区间

    1-142aa

  • 氨基酸序列

    MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDWCCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNLGTYNRKYAHYPNKLCTGPTPPC

  • 分子量

    16.1kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

PLA2G2E, or Phospholipase A2 Group IIE, is a member of the phospholipase A2 family and plays a crucial role in various physiological processes, including inflammation and cell signaling. This enzyme is primarily found in human tissues such as the pancreas, and its activity is linked to the metabolism of membrane phospholipids, leading to the production of bioactive lipids that modulate inflammatory responses. Research has shown that PLA2G2E can influence the progression of diseases, including cancer, cardiovascular conditions, and autoimmune disorders. Due to its significant role in these pathological processes, PLA2G2E is of great interest as a potential therapeutic target and biomarker for disease diagnosis. The study of recombinant forms of PLA2G2E allows for a better understanding of its biochemical properties, enzymatic mechanisms, and interactions with other cellular components. Moreover, the expression of recombinant PLA2G2E in appropriate systems provides a platform for drug screening and the development of enzyme inhibitors, which may alleviate inflammation and improve clinical outcomes in various diseases. Recent advances in molecular biology and protein engineering have facilitated the production of active recombinant PLA2G2E, paving the way for in-depth functional studies that could elucidate its role in disease pathology and therapeutic applications. As research continues to unfold, the understanding of PLA2G2E's structure-function relationship will further enhance its potential use in clinical settings, making it a focal point of study in the field of biochemistry and pharmacology.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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