Analytical Data
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基因名
NPM2
- Application
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别名
NPM2;Nucleoplasmin-2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86SE8
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表达区间
1-214aa
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氨基酸序列
MNLSSASSTE EKAVTTVLWG CELSQERRTW TFRPQLEGKQ SCRLLLHTIC LGEKAKEEMH RVEILPPANQ EDKKMQPVTI ASLQASVLPM VSMVGVQLSP PVTFQLRAGS GPVFLSGQER YEASDLTWEE EEEEEGEEEE EEEEDDEDED ADISLEEQSP VKQVKRLVPQ KQASVAKKKK LEKEEEEIRA SVRDKSPVKK AKATARAKKP GFKK
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NPM2 (Nucleophosmin 2) is a nucleolar protein that plays a crucial role in various cellular processes, including ribosome biogenesis, cell proliferation, and stress response. Recent studies have highlighted its importance in developmental biology and its potential involvement in various diseases, particularly cancer. The ability of NPM2 to bind RNA and other proteins suggests that it may function as a critical regulator of gene expression and RNA metabolism. Research into the recombinant production of NPM2 proteins has gained traction due to the need for understanding its molecular mechanisms and interactions in vivo. Producing NPM2 in a recombinant form allows researchers to investigate its structure, function, and interaction with other cellular components in a controlled environment. Moreover, studying the biochemical properties of NPM2, such as its post-translational modifications and binding affinities, can reveal insights into its role in tumorigenesis and cellular stress responses. As a result, developing reliable methods for the purification and characterization of NPM2 provides valuable tools for exploring its biological functions and potential therapeutic implications. This growing body of research underscores the significance of NPM2 not only in fundamental biology but also in the development of innovative strategies aimed at targeting this protein in disease contexts.












