Analytical Data
-
基因名
SNRPD1
- Application
-
别名
SNRPD1；SNRPD1；Small nuclear ribonucleoProtein Sm D2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P62314
-
表达区间
1-119aa
-
氨基酸序列
MKLVRFLMKL SHETVTIELK NGTQVHGTIT GVDVSMNTHL KAVKMTLKNR EPVQLETLSI RGNNIRYFIL PDSLPLDTLL VDVEPKVKSK KREAVAGRGR GRGRGRGRGR GRGRGGPRR
-
分子量
13.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human NFKBID Protein，His
Cat：PA1000-2142
Recombinant Human LRRC29 Protein，GST
Cat：PA2000-9063
Protein Description
SNRPD1, a crucial component of the spliceosomal machinery, plays a vital role in pre-mRNA splicing by forming part of the small nuclear ribonucleoproteins (snRNPs). These snRNPs are essential for the removal of introns from precursor mRNAs, a process that is critical for the accurate expression of eukaryotic genes. Researchers have increasingly focused on SNRPD1 due to its implications in various cellular processes and its association with certain diseases, including cancer and genetic disorders. The study of SNRPD1 recombinant protein allows for in-depth analysis of its structure, function, and interaction with other spliceosomal components, which can provide insights into splicing mechanisms. Additionally, the production of SNRPD1 as a recombinant protein facilitates the development of potential therapeutic strategies aimed at modulating splicing for disease intervention. This research area is particularly significant given the emerging recognition of alternative splicing as a major regulatory mechanism affecting gene expression and cellular function. Investigating SNRPD1 not only enhances our understanding of fundamental cellular processes but may also lead to novel therapeutic approaches for diseases linked to splicing dysfunction.
