Analytical Data
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Gene name
PINP
- Application
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Alternative Names
PINP；2S albumin seed storage Protein PINP1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A0A0K3AVY3
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Expression Region
1-164aa
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AA Sequence
MGVFSSPMSTLRWVTLFAALLSLLEWGTAHEDIVMDGDQVVQQQGRSCDPQRLSACRDYLQRRREQPSERCCEELQRMSPHCRCRAIERALDQSQSYDSSTDSDSQDGAPLNQRRRRRGEGRGREEEEAVERAEELPNRCNLRESPRRCDIRRHSRYSIIGGSD
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Molecular Weight
18.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PINP (Procollagen type I N-terminal propeptide) is a biomarker associated with the synthesis of type I collagen, which plays a crucial role in bone formation and remodeling. Research into PINP and its recombinant protein form has gained attention due to its potential applications in diagnosing and monitoring bone-related conditions, such as osteoporosis and other metabolic bone diseases. As a product of collagen synthesis, PINP levels reflect the activity of osteoblasts, the cells responsible for new bone formation. Elevated levels of PINP can indicate increased bone formation, whereas low levels may suggest suppressed osteoblast activity. The development of recombinant PINP provides a standardized and reliable means to study its biological functions and mechanisms in various physiological and pathological contexts. Furthermore, understanding PINP's role in bone health could lead to the identification of novel therapeutic targets and strategies for enhancing bone regeneration and preventing osteoporosis. Research in this area not only aims to clarify the biochemical pathways involved in collagen synthesis but also seeks to establish the clinical relevance of PINP measurement in evaluating treatment efficacy in bone diseases. Overall, the study of PINP and its recombinant forms represents a promising frontier in biomedical research, with implications for improving patient outcomes in skeletal health.
