Analytical Data
-
Gene name
LNX2
- Application
-
Alternative Names
FLJ12933; FLJ23932; FLJ38000; Ligand of Numb protein X 2; LNX 2; LNX2; LNX2_HUMAN; MGC46315; Numb binding protein 2; Numb-binding protein 2; PDZ domain containing ring finger 1; PDZ domain containing RING finger protein 1; PDZ domain-containing RING finger protein 1; PDZRN 1; PDZRN1
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q8N448
-
Expression Region
1-690aa
-
AA Sequence
MGTTSDEMVSVEQTSSSSLNPLCFECGQQHWTRENHLYNYQNEVDDDLVCHICLQPLLQPLDTPRGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSSVCKDVMQRCDLEAHLKNRCPGASHRRVALERRKTSRTQAEIENENGPTLLDPAGTLSPEADCLGTGAVPVERHLTSASLPTWSEEPGLDNPAFEESAGADTTQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYNISNVSHNYARAVLSQPCNTLHLTVLRERRFGNRAHNHSDSNSPREEIFQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKYGTPELAAQIIQASGERVNLTIARPGKPQPGNTIREAGNHSSSSQHHTPPPYYSRPSSHKDLTQCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVALKALEVQIVEEATQNAEEQPSTFSENEYDASWSPSWVMWLGLPSTLHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV
-
Molecular Weight
102.3 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LNX2 (Ligand of Numb-protein X 2) is a protein that belongs to the LNX family and has gained attention in recent years due to its potential roles in various cellular processes, particularly in neuronal development and signaling pathways. Research into LNX2 has revealed its involvement in regulating the differentiation and proliferation of neuronal precursor cells, which is crucial for normal brain development and function. Additionally, LNX2 is thought to play a significant role in synaptic transmission and plasticity, contributing to learning and memory processes. Furthermore, the dysregulation of LNX2 has been implicated in several neurodegenerative diseases and cancers, highlighting its potential as a therapeutic target. As a result, the study of LNX2 recombinant proteins has become pivotal, as they provide essential tools for elucidating the protein's structure-function relationships, interaction networks, and biological roles. Investigating LNX2 through recombinant protein techniques may also pave the way for novel diagnostic and therapeutic strategies, particularly in neurobiology and oncology, where understanding the molecular mechanisms underlying disease pathogenesis is critical for developing effective interventions. Overall, the research into LNX2 and its recombinant proteins is an emerging field that holds promise for advancing our knowledge of cellular signaling mechanisms and their implications in health and disease.
