Analytical Data
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Gene name
LMBR1L
- Application
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Alternative Names
LMBR1L; KIAA1174; LIMR; UNQ458/PRO783Protein LMBR1L; Limb region 1 protein homolog-like; Lipocalin-1-interacting membrane receptor; LIMR
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6UX01
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Expression Region
1-489aa
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AA Sequence
MEAPDYEVLSVREQLFHERIRECIISTLLFATLYILCHIFLTRFKKPAEFTTVDDEDATVNKIALELCTFTLAIALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNKANRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLYCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGTSLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRSLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPQASRKTQHQ
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Molecular Weight
81.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LMBR1L, a member of the Limb-Bud Marker 1-like gene family, has garnered significant attention in recent years due to its potential roles in both developmental biology and disease mechanisms. Initially identified in the context of limb development, LMBR1L is known to be involved in various cellular processes, including cell signaling, tissue differentiation, and organogenesis. Its expression is particularly prominent in embryonic tissues and has been linked to the regulation of key developmental pathways, such as the Sonic Hedgehog (Shh) signaling pathway, which is critical for limb and central nervous system development. The dysregulation of LMBR1L has been implicated in congenital malformations and several pathological conditions, including cancer, where altered signaling has been associated with tumor progression and metastasis. Research into the recombinant form of LMBR1L protein aims to elucidate its functional roles and interactions at the molecular level. By producing and characterizing LMBR1L recombinant proteins, scientists can explore their structural properties, biochemical activities, and potential therapeutic applications. This research not only contributes to our understanding of LMBR1L's role in normal physiological processes but also paves the way for developing novel strategies to target associated diseases. As such, the study of LMBR1L recombinant protein is a vibrant area of investigation that holds promise for both basic research and clinical advancements.
