Analytical Data
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Gene name
ANG-3
- Application
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Alternative Names
ANG-3；ANG3；ANG4；Angiopoietin-4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95841
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Expression Region
24-491aa
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AA Sequence
GQFKIKK INQRRYPRAT DGKEEAKKCA YTFLVPEQRI TGPICVNTKG QDASTIKDMI TRMDLENLKD VLSRQKREID VLQLVVDVDG NIVNEVKLLR KESRNMNSRV TQLYMQLLHE IIRKRDNSLE LSQLENKILN VTTEMLKMAT RYRELEVKYA SLTDLVNNQS VMITLLEEQC LRIFSRQDTH VSPPLVQVVP QHIPNSQQYT PGLLGGNEIQ RDPGYPRDLM PPPDLATSPT KSPFKIPPVT FINEGPFKDC QQAKEAGHSV SGIYMIKPEN SNGPMQLWCE NSLDPGGWTV IQKRTDGSVN FFRNWENYKK GFGNIDGEYW LGLENIYMLS NQDNYKLLIE LEDWSDKKVY AEYSSFRLEP ESEFYRLRLG TYQGNAGDSM MWHNGKQFTT LDRDKDMYAG NCAHFHKGGW WYNACAHSNL NGVWYRGGHY RSKHQDGIFW AEYRGGSYSL RAVQMMIKPI D
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Molecular Weight
56.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ANG-3, also known as angiogenin-3, is a member of the angiogenin family of proteins, which are primarily known for their roles in angiogenesis, the formation of new blood vessels. The study of ANG-3 has gained significant interest due to its potential implications in various physiological and pathological processes, including cancer progression, neurodegenerative diseases, and tissue repair. Unlike its better-studied counterparts, such as angiogenin (ANG-1), the functional mechanisms and specific roles of ANG-3 remain less understood. Research indicates that ANG-3 may have unique angiogenic properties, possibly influencing cellular proliferation and migration in different types of tissues. Additionally, its expression patterns in various cancers suggest a potential role in tumor growth and metastasis, making it a candidate for therapeutic targeting. Understanding the structure-function relationship of ANG-3 through studies involving recombinant protein production and characterization could provide insights into its biological activities and contributions to disease mechanisms. Such research is crucial for developing novel therapeutic strategies aimed at modulating its activity to either inhibit cancer progression or promote tissue regeneration. Overall, the study of ANG-3 encompasses a multidisciplinary approach, integrating biotechnology, molecular biology, and clinical research to elucidate its function and therapeutic potential in human health and disease.
