Analytical Data
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Gene name
CD32
- Application
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Alternative Names
CD32；CD32；FCG2；IGFR2；Low affinity immunoglobulin gamma Fc region receptor II-b
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P12318
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Expression Region
34-216aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQAAPP KAVLKLEPPW INVLQEDSVT LTCQGARSPE SDSIQWFHNG NLIPTHTQPS YRFKANNNDS GEYTCQTGQT SLSDPVHLTV LSEWLVLQTP HLEFQEGETI MLRCHSWKDK PLVKVTFFQN GKSQKFSRLD PTFSIPQANH SHSGDYHCTG NIGYTLFSSK PVTITVQVPS MGSSSPMG
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Molecular Weight
23 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CD32, also known as FcγRII, is a low-affinity receptor for IgG that plays a crucial role in the immune response by mediating the phagocytosis of pathogens and the regulation of antibody-mediated effector functions. Its significance in various diseases, including autoimmune disorders, infections, and cancer, has prompted extensive research into its biological functions and therapeutic potential. Recombinant CD32 proteins have been developed to study its interactions with IgG antibodies in detail, as well as to elucidate its signaling pathways. These recombinant proteins serve as valuable tools in immunological research, enabling researchers to investigate the receptor's function in different cellular contexts, assess its role in disease mechanisms, and explore potential applications in therapies, such as enhancing antibody-dependent cellular cytotoxicity (ADCC) or modulating immune responses. Understanding the structural and functional properties of CD32 is essential for developing targeted interventions that could improve patient outcomes in various clinical settings.
