Analytical Data
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基因名
METAP1D
- Application
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别名
METAP1D;MAP1D;Methionine aminopeptidase 1D. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UB28
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表达区间
20-335aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSSSPLNHIYLHKQSSSQQRRNFFFRRQRDISHSIVLPAAVSSAHPVPK HIKKPDYVTTGIVPDWGDSIEVKNEDQIQGLHQACQLARHVLLLAGKSLK VDMTTEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDS RPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDE AIAACRAGAPFSVIGNTISHITHQNGFQVCPHFVGHGIGSYFHGHPEIWH HANDSDLPMEEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEH TVLITSRGAQILTKLPHEA
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
METAP1D is a member of the methionine aminopeptidase (MetAP) family, which plays a crucial role in protein maturation by catalyzing the removal of the N-terminal methionine from nascent polypeptides. The study of METAP1D has gained significance due to its involvement in various cellular processes, including cell proliferation, apoptosis, and differentiation. Abnormal expression or activity of METAP1D has been linked to several diseases, including cancer, where it may affect tumor growth and cancer cell survival. Additionally, METAP1D's enzymatic function is of interest in therapeutic contexts, such as developing inhibitors that could be used to target cancer cells selectively. Research on the recombinant expression of METAP1D can advance our understanding of its structure-function relationship and provide insights into potential therapeutic applications. The generation and characterization of METAP1D recombinant protein can facilitate drug design and development, as well as contribute to the elucidation of its biological role in disease mechanisms. Overall, METAP1D serves as a compelling target for both basic research and clinical applications, making it a significant focus in the field of molecular biology and pharmacology.
