Analytical Data
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基因名
TPOR
- Application
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别名
TPOR；TPOR；Thrombopoietin receptor
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P40238
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表达区间
22-353aa
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氨基酸序列
QVSSQDVSLLASDSEPLKCFSRTFEDLTCFWDEEEAAPSGTYQLLYAYPR EKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFPLHLWVKNVFLNQTRT QRVLFVDSVGLPAPPSIIKAMGGSQPGELQISWEEPAPEISDFLRYELRY GPRDPKNSTGPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDG PKQTSPSREASALTAEGGSCLISGLQPGNSYWLQLRSEPDGISLGGSWGS WSLPVTVDLPGDAVALGLQCFTLDLKNVTCQWQQQDHASSQGFFYHSRAR CCPRDRYPIWENCEEEEKTNPGLQTPQFSRCH
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TPOR (Thrombopoietin receptor) is a crucial component in the regulation of megakaryocyte differentiation and platelet production. As a primary receptor for thrombopoietin, it plays a significant role in hematopoiesis and maintaining platelet homeostasis. Dysregulation of TPOR has been implicated in various hematological disorders, including thrombocytopenia and essential thrombocythemia. Recent studies have aimed to characterize TPOR at the molecular level, focusing on its structure and function to understand the mechanisms that govern its activity. The development of TPOR recombinant proteins has provided valuable tools for both basic research and therapeutic applications, allowing scientists to explore its signaling pathways and interactions with other cellular components. Furthermore, engineered TPOR variants are being investigated for their potential in treating disorders related to platelet production. By enhancing our understanding of TPOR and its role in platelet biology, researchers hope to pave the way for innovative treatments for blood-related diseases, making it a pivotal area of study in molecular and cellular biology. The insights gained from TPOR research hold promise for advancing therapeutic strategies targeting platelet disorders and improving patient outcomes.
