Cat: PA1000-1937

Recombinant Human MEIS3 Protein,His

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Analytical Data

  • Gene name

    MEIS3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    MEIS3;MRG2;Homeobox Protein Meis3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q99687

  • Expression Region

    1-358aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMARRYDE LPHYPGIVDG PAALASFPET VPAVPGPYGP HRPPQPLPPG LDSDGLKREK DEIYGHPLFP LLALVFEKCE LATCSPRDGA GAGLGTPPGG DVCSSDSFNE DIAAFAKQVR SERPLFSSNP ELDNLMIQAI QVLRFHLLEL EKGKMPIDLV IEDRDGGCRE DFEDYPASCP SLPDQNNMWI RDHEDSGSVH LGTPGPSSGG LASQSGDNSS DQGDGLDTSV ASPSSGGEDE DLDQERRRNK KRGIFPKVAT NIMRAWLFQH LSHPYPSEEQ KKQLAQDTGL TILQVNNWFI NARRRIVQPM IDQSNRTGQG AAFSPEGQPI GGYTETQPHV AVRPPGSVGM SLNLEGEWHY L

  • Molecular Weight

    41 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

MEIS3 is a member of the Meis family of transcription factors, which play crucial roles in embryonic development, organogenesis, and tissue homeostasis. Recent studies have highlighted MEIS3's involvement in various cellular processes, including differentiation, proliferation, and apoptosis. Given its pivotal role in stem cell maintenance and cancer biology, understanding the structure and function of MEIS3 is of significant interest to researchers. The protein is known to interact with other transcription factors and epigenetic regulators, influencing gene expression patterns. Moreover, aberrant expression of MEIS3 has been implicated in several cancers, suggesting that it may serve as a potential therapeutic target. The reconstitution of MEIS3 in vitro offers valuable insights into its functional domains and regulatory mechanisms, shedding light on its contribution to developmental pathways and disease states. Continued research on MEIS3 not only aims to elucidate its biological roles but also seeks to identify potential pathways for intervention in tumors or regenerative medicine, making it a focus of ongoing scientific investigation in the fields of developmental biology and oncology.

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