Analytical Data
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Gene name
KRT79
- Application
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Alternative Names
KRT79; K6L; KB38; KRT6L; Keratin; type II cytoskeletal 79; Cytokeratin-79; CK-79; Keratin-6-like; Keratin-6L; Keratin-79; K79; Type-II keratin Kb38
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5XKE5
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Expression Region
1-535aa
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AA Sequence
MRSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAGTSILRKTTTVKTSSQRY
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Molecular Weight
84.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KRT79, or Keratin 79, is a member of the keratin family of proteins, which play a crucial role in the structural integrity and function of epithelial cells. Research into KRT79 has gained significance due to its potential involvement in skin diseases, particularly disorders related to keratinization and skin barrier function. Understanding the molecular mechanisms underlying KRT79 expression and regulation can provide insights into various dermatological conditions, including ichthyosis and psoriasis. Additionally, since keratins are critical for the integrity of hair and nails, studying KRT79 may also reveal important information about hair follicle biology and related disorders. Recent advances in genomics and proteomics have facilitated the characterization of KRT79, allowing researchers to explore its role in cellular processes, interaction with other proteins, and its potential as a biomarker for disease. This research is further underscored by the growing interest in targeted therapies for skin disorders, whereby manipulating keratin expression may offer new avenues for treatment. Thus, KRT79 presents a compelling target for both fundamental research and clinical applications in dermatology.
