Analytical Data
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Gene name
GSSG
- Application
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Alternative Names
GSSG；GGTLA1；Glutathione hydrolase 5 proenzyme
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P36269
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Expression Region
1-586aa
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AA Sequence
MARGYGATVSLVLLGLGLALAVIVLAVVLSRHQAPCGPQAFAHAAVAADSKVCSDIGRAILQQQGSPVDATIAALVCTSVVNPQSMGLGGGVIFTIYNVTTGKVEVINARETVPASHAPSLLDQCAQALPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLRGGHVVAPVLSRFLHNSILRPSLQASTLRQLFFNGTEPLRPQDPLPWPALATTLETVATEGVEVFYTGRLGQMLVEDIAKEGSQLTLQDLAKFQPEVVDALEVPLGDYTLYSPPPPAGGAILSFILNVLRGFNFSTESMARPEGRVNVYHHLVETLKFAKGQRWRLGDPRSHPKLQNASRDLLGETLAQLIRQQIDGRGDHQLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRTGIILNNELLDLCERCPRGSGTTPSPVSGDRVGGAPGRCWPPVPGERSPSSMVPSILINKAQGSKLVIGGAGGELIISAVAQAIMSKLWLGFDLRAAIAAPILHVNSKGCVEYEPNFSQEVQRGLQDRGQNQTQRPFFLNVVQAVSQEGACVYAVSDLRKSGEAAGY
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Molecular Weight
62.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GSSG (glutathione disulfide) is a crucial component in the cellular redox state, representing the oxidized form of glutathione, an important antioxidant that helps maintain cellular health by neutralizing reactive oxygen species. Researchers have been increasingly interested in GSSG and its role in various biological processes, including cellular signaling, apoptosis, and the regulation of immune responses. The study of GSSG-recombinant proteins offers insights into its biological relevance, allowing for the examination of its interactions with proteins, enzymes, and other cellular components in controlled environments. By engineering GSSG in recombinant systems, such as bacteria or yeast, scientists aim to elucidate the mechanisms underlying redox regulation and stress responses in cells. Furthermore, understanding GSSG's role at a molecular level can aid in the development of therapeutic interventions for diseases associated with oxidative stress, such as cancer and neurodegenerative disorders. The recombinant production of GSSG also paves the way for potential biotechnological applications, including the design of antioxidants and the enhancement of storage stability in pharmaceutical formulations. Through these studies, researchers are not only expanding our fundamental understanding of cellular biochemistry but also exploring practical applications that could significantly impact health and medicine.
