Analytical Data
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基因名
KIAA1443
- Application
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别名
HOMEZ. KIAA1443
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IX15
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表达区间
1-526aa
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氨基酸序列
MPPNKEASGLSSSPAGLICLPPISEELQLVWTQAAQTSELDSNEHLLKTFSYFPYPSLADIALLCLRYGLQMEKVKTWFMAQRLRCGISWSSEEIEETRARVVYRRDQLHFKSLLSFTHHAGRPPEEVPPPPVPAPEQVGIGIGPPTLSKPTQTKGLKVEPEEPSQMPPLPQSHQKLKESLMTPGSGAFPYQSDFWQHLQSSGLSKEQAGRGPNQSHGIGTASWNHSTTVPQPQARDKPPPIALIASSCKEESASSVTPSSSSTSSSFQVLANGATAASKPLQPLGCVPQSVSPSEQALPPHLEPAWPQGLRHNSVPGRVGPTEYLSPDMQRQRKTKRKTKEQLAILKSFFLQCQWARREDYQKLEQITGLPRPEIIQWFGDTRYALKHGQLKWFRDNAVPGAPSFQDPAIPTPPPSTRSLNERAETPPLPIPPPPPDIQPLERYWAAHQQLRETDIPQLSQASRLSTQQVLDWFDSRLPQPAEVVVCLDEEEEEEEEELPEDDEEEEEEEEEDDDDDDDDVIIQD
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分子量
85.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA1443, also known as NUTF2, is a gene that has garnered interest in the field of molecular biology due to its potential role in cellular processes and disease mechanisms. Initially identified through large-scale sequencing projects, KIAA1443’s function remains largely unexplored. However, preliminary studies suggest that it may be involved in nucleocytoplasmic transport, influencing the localization of proteins between the nucleus and cytoplasm, which is crucial for various cellular functions. Dysregulation of nucleocytoplasmic transport has been implicated in several diseases, including cancer and neurodegenerative disorders. Recent research has indicated that KIAA1443 may interact with key proteins involved in these processes, highlighting its potential as a biomarker or therapeutic target. Additionally, the structural characteristics of the KIAA1443 protein may provide insights into its functional mechanisms and interactions within the cell. Given the growing interest in the role of novel genes and proteins in health and disease, understanding KIAA1443's functions and mechanisms could pave the way for new diagnostic and therapeutic strategies. Ongoing studies aim to elucidate the biological significance of KIAA1443 and its potential implications in disease pathways, contributing to a broader understanding of cellular dynamics and the intricate network of protein interactions that govern cellular behavior.
