Analytical Data
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Gene name
KIAA1257
- Application
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Alternative Names
KIAA1257; Uncharacterized protein KIAA1257
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9ULG3
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Expression Region
1-409aa
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AA Sequence
MSLHAWEWEE DPASIEPISS ITSFYQSTSE CDVEEHLKAK ARAQESDSDR PCSSIESSSE PASTFSSDVP HVVPCKFTIS LAFPVNMGQK GKYASLIEKY KKHPKTDSSV TKMRRFYHIE YFLLPDDEEP KKVDILLFPM VAKVFLESGV KTVKPWHEGD KAWVSWEQTF NITVTKELLK KINFHKITLR LWNTKDKMSR KVRYYRLKTA GFTDDVGAFH KSEVRHLVLN QRKLSEQGIE NTNIVREESN QEHPPGKQEK TEKHPKSLQG SHQAEPETSS KNSEEYEKSL KMDDSSTIQW SVSRTPTISL AGASMMEIKE LIESESLSSL TNILDRQRSQ IKGKDSEGRR KIQRRHKKPL AEEEADPTLT GPRKQSAFSI QLAVMPLLAG THCLPCSQQL LLVLWPERP
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Molecular Weight
46.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA1257, a gene located on chromosome 3, encodes a protein that is implicated in various cellular processes, including cell proliferation and differentiation. Research has shown that KIAA1257 is involved in the regulation of developmental pathways and may play a role in certain cancers. Its expression levels can be altered in various tumor types, suggesting a potential link to cancer biology. Understanding the function and mechanisms of KIAA1257 is critical for deciphering its role in oncogenesis, as well as its potential as a biomarker for cancer diagnosis or prognosis. Recent studies have focused on the recombinant protein of KIAA1257, enabling researchers to investigate its structure and function more thoroughly. By expressing KIAA1257 as a recombinant protein, scientists can analyze its interactions with other proteins, assess its enzymatic activity, and evaluate its potential therapeutic applications. Furthermore, exploring the signaling pathways influenced by KIAA1257 may provide insights into its contributions to tumor microenvironments. Overall, the study of KIAA1257 and its recombinant protein is vital for advancing our understanding of cancer mechanisms and developing targeted treatment strategies.











