Analytical Data
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基因名
KLHDC8B
- Application
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别名
KLHDC8B;Kelch domain-containing Protein 8B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IXV7
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表达区间
1-354aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMSAGGGR AFAWQVFPPM PTCRVYGTVA HQDGHLLVLG GCGRAGLPLD TAETLDMASH TWLALAPLPT ARAGAAAVVL GKQVLVVGGV DEVQSPVAAV EAFLMDEGRW ERRATLPQAA MGVATVERDG MVYALGGMGP DTAPQAQVRV YEPRRDCWLS LPSMPTPCYG ASTFLHGNKI YVLGGRQGKL PVTAFEAFDL EARTWTRHPS LPSRRAFAGC AMAEGSVFSL GGLQQPGPHN FYSRPHFVNT VEMFDLEHGS WTKLPRSLRM RDKRADFVVG SLGGHIVAIG GLGNQPCPLG SVESFSLARR RWEALPAMPT ARCSCSSLQA GPRLFVIGGV AQGPSQAVEA LCLRDGV
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分子量
40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLHDC8B (Kelch-like protein 8B) is a member of the Kelch protein family, known for its role in mediating protein-protein interactions and participating in various cellular processes, including cytoskeletal organization, signal transduction, and immune response regulation. Research into KLHDC8B has gained traction due to its potential implications in disease mechanisms, particularly in cancers and neurodegenerative disorders. Initial studies have indicated that KLHDC8B may play a role in promoting cell proliferation and survival, suggesting its involvement in tumorigenesis. Additionally, its expression patterns in specific tissues and cellular contexts highlight its potential as a biomarker for certain pathological conditions. Recent advances in recombinant protein technology have facilitated the production of KLHDC8B for functional studies, enabling researchers to elucidate its structure and biological activities. By characterizing the interactions of KLHDC8B with other cellular partners, scientists aim to clarify its functional roles and regulatory mechanisms. Understanding KLHDC8B's involvement in cellular pathways could provide insights into developing targeted therapeutic strategies for diseases where this protein is implicated. Overall, the study of KLHDC8B as a recombinant protein is critical to unraveling its biological significance and potential as a therapeutic target.
