Analytical Data
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基因名
KIAA0701
- Application
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别名
BLTP3B. KIAA0701. SHIP164. UHRF1BP1L
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A0JNW5
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表达区间
1-522aa
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氨基酸序列
MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNAHWEHGDLRFTRIQDPQRGEVLTFKEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSMAPEPTQSSIVVASAQQVKTTQTSNAPDVNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHAKEKESNRRITGGAMQLSFTQLTIDYYPYHKAGDSCNHWMYFSDATKTKNGWANELLHEFECNVEMLKQAVKDHNVGSPPKSPTHASPQHTQTEKDYPLKGTCRTPSVLSQQSKAKLMSSSVVVRLADFNIYQVSTAEQCRSSPKSMICCNKKSLYLPQEMSAVYIEFTEYYYPDGKDFPTAFLSR
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分子量
82.94 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA0701, also known as MCRS1 (microtubule catastrophe and rescue site 1), is a protein implicated in various cellular processes, including cell proliferation, differentiation, and response to stress. Initially identified through gene cloning techniques, KIAA0701 has garnered attention for its potential role in cancer biology, particularly in relation to tumor progression and metastasis. Research indicates that KIAA0701 participates in the regulation of the cytoskeleton and cell cycle, functioning as a critical mediator in signal transduction pathways. Moreover, abnormal expression of KIAA0701 has been linked to several malignancies, making it a candidate for therapeutic targeting and biomarker development. Its involvement in cellular stress response mechanisms also highlights its importance in understanding how cancer cells adapt to hostile environments. Recent studies have focused on the protein's structural characteristics and functional domains, utilizing recombinant protein techniques to produce and analyze KIAA0701 in vitro. This research aims to elucidate its mechanistic roles and interactions within the cellular context, paving the way for novel strategies in cancer treatment and personalized medicine approaches. Overall, the ongoing investigation of KIAA0701 reaffirms the significance of this protein in both fundamental biology and clinical applications, marking it as a promising target for future studies in cancer therapeutics.
