Analytical Data
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Gene name
KIAA0409
- Application
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Alternative Names
Cerebral protein 1; hypothetical protein LOC23378; KIAA0409; NML; Nucleomethylin; Ribosomal RNA processing 8 methyltransferase homolog; Ribosomal RNA processing 8. methyltransferase. homolog (yeast); Ribosomal RNA processing protein 8
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43159
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Expression Region
1-456aa
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AA Sequence
MFEEPEWAEAAPVAAGLGPVISRPPPAASSQNKGSKRRQLLATLRALEAASLSQHPPSLCISDSEEEEEERKKKCPKKASFASASAEVGKKGKKKCQKQGPPCSDSEEEVERKKKCHKQALVGSDSAEDEKRKRKCQKHAPINSAQHLDNVDQTGPKAWKGSTTNDPPKQSPGSTSPKPPHTLSRKQWRNRQKNKRRCKNKFQPPQVPDQAPAEAPTEKTEVSPVPRTDSHEARAGALRARMAQRLDGARFRYLNEQLYSGPSSAAQRLFQEDPEAFLLYHRGFQSQVKKWPLQPVDRIARDLRQRPASLVVADFGCGDCRLASSIRNPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKPGGLLKVAEVSSRFEDVRTFLRAVTKLGFKIVSKDLTNSHFFLFDFQKTGPPLVGPKAQLSGLQLQPCLYKRR
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Molecular Weight
77.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA0409 is a largely unexplored protein that has garnered interest in the field of molecular biology and biomedicine due to its potential roles in various cellular processes. Initially identified through genomic studies, KIAA0409 has been implicated in critical pathways associated with cell proliferation, differentiation, and survival. Its expression patterns are observed in various human tissues, suggesting a possible involvement in physiological as well as pathological processes. Recent studies have pointed to KIAA0409's potential connection with cancer development, particularly in the modulation of tumor growth and metastasis, which highlights its significance as a prospective biomarker and therapeutic target. The emphasis on understanding KIAA0409's structure and function is paramount, as it may contribute to systemic disease mechanisms, including metabolic disorders and neurological conditions. As the landscape of proteomics evolves, unraveling the intricacies of KIAA0409 through techniques like recombinant protein expression, functional assays, and protein interaction studies may offer valuable insights into its biological roles and clinical implications. This research could ultimately pave the way for novel diagnostic and therapeutic strategies, harnessing KIAA0409's properties to improve patient outcomes in various diseases.
