Analytical Data
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基因名
KCTD17
- Application
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别名
BTB; BTB/POZ domain-containing protein KCTD17; FLJ12242; FLJ98761; KCD17_HUMAN; KCTD17; Potassium channel tetramerisation domain containing 17; POZ domain-containing protein KCTD17; RP5-1170K4.4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N5Z5
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表达区间
1-321aa
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氨基酸序列
MQTPRPAMRM EAGEAAPPAG AGGRAAGGWG KWVRLNVGGT VFLTTRQTLC REQKSFLSRL CQGEELQSDR DETGAYLIDR DPTYFGPILN FLRHGKLVLD KDMAEEGVLE EAEFYNIGPL IRIIKDRMEE KDYTVTQVPP KHVYRVLQCQ EEELTQMVST MSDGWRFEQL VNIGSSYNYG SEDQAEFLCV VSKELHSTPN GLSSESSRKT KSTEEQLEEQ QQQEEEVEEV EVEQVQVEAD AQEKAQSSQD PANLFSLPPL PPPPLPAGGS RPHPLRPEAE LAVRASPRPL ARPQSCHPCC YKPEAPGCEA PDHLQGLGVP I
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分子量
34.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KCTD17 is a member of the potassium channel tetramerization domain (KCTD) protein family, which is involved in various cellular processes, including ion channel regulation, signal transduction, and the modulation of cellular homeostasis. Research on KCTD17 has gained momentum due to its potential roles in neurodevelopment and its implications in various diseases, including cancer and neurodegenerative disorders. The ability of KCTD17 to interact with a variety of protein partners and its localization in the brain suggests a critical function in the central nervous system. The study of KCTD17, particularly in the context of recombinant protein production, allows for detailed examination of its structural and functional properties. Understanding the mechanism by which KCTD17 operates can reveal insights into its biological significance and therapeutic potential. Recent advances in protein expression systems and purification techniques have facilitated the generation of recombinant KCTD17, enabling researchers to investigate its interactions and contributions to cellular mechanisms. The ongoing exploration of KCTD17's role highlights the importance of this protein in health and disease, positioning it as a compelling target for future therapeutic strategies.
