Analytical Data
-
Gene name
KCTD16
- Application
-
Alternative Names
BTB/POZ domain containing protein KCTD16; BTB/POZ domain-containing protein KCTD16; DKFZp781A1155; KCD16_HUMAN; KCTD16; KIAA1317; MGC138167; Potassium channel tetramerisation domain containing 16
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q68DU8
-
Expression Region
1-428aa
-
AA Sequence
MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKEGESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMRRKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL
-
Molecular Weight
47.1 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KCTD16, or KCTD domain-containing protein 16, is part of the KCTD protein family, which is characterized by the presence of the KCTD domain known for its involvement in diverse biological processes. Research into KCTD16 has gained momentum due to its potential roles in neuronal development and function, as well as its implications in various diseases. Specifically, KCTD16 is thought to influence synaptic signaling and neuronal excitability, impacting learning and memory. The protein has been associated with the regulation of ion channels and has been implicated in neurodevelopmental disorders, making it a candidate for further exploration in the context of neurobiology. Furthermore, studies have suggested that KCTD16 may be involved in cellular responses to stress or injury, positioning it as a significant factor in neuroprotection and repair mechanisms. Understanding the structural and functional properties of KCTD16, particularly through the generation of recombinant proteins, could provide insights into its biological functions and therapeutic potential. The study of KCTD16's interactions and pathways offers promising avenues for addressing neurological conditions and enhancing our understanding of synaptic dynamics. The ongoing research aims to elucidate the molecular mechanisms by which KCTD16 influences neuronal activity and its broader implications in health and disease.
