Analytical Data
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基因名
KCTD10
- Application
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别名
KCTD10; ULR061; MSTP028BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3; hBACURD3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H3F6
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表达区间
1-313aa
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氨基酸序列
MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRIHIKRPDDRAHLHQ
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分子量
61.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KCTD10, a member of the KCTD protein family, has garnered interest in biomedical research due to its potential roles in cellular signaling and pathophysiological processes. This protein contains a BC box domain, suggesting its involvement in the regulation of substrate recognition for ubiquitination. Recent studies have implicated KCTD10 in various cellular functions, including modulating neuronal signaling pathways and influencing cellular proliferation and differentiation. Abnormal expression of KCTD10 has been associated with several diseases, including neurodegenerative disorders and certain cancers, highlighting its significance as a potential biomarker and therapeutic target. Understanding the molecular mechanisms underlying KCTD10's function may provide insights into disease progression and open avenues for novel treatment strategies. The production and characterization of recombinant KCTD10 is instrumental for mechanistic studies and could facilitate the exploration of its role in various biological contexts. As a result, research focused on KCTD10 not only sheds light on fundamental biological processes but also holds promise for innovative therapeutic developments.
