Analytical Data
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基因名
IL9
- Application
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别名
IL9;Interleukin-9
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P15248
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表达区间
19-144aa
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氨基酸序列
MQGCPTLAGI LDINFLINKM QEDPASKCHC SANVTSCLCL GIPSDNCTRP CFSERLSQMT NTTMQTRYPL IFSRVKKSVE VLKNNKCPYF SCEQPCNQTT AGNALTFLKS LLEIFQKEKM RGMRGKI
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分子量
15 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Interleukin 9 (IL-9) is a cytokine that plays a crucial role in the regulation of immune responses, particularly in the context of allergic diseases and asthma. It is primarily produced by a subset of CD4+ T helper cells, known as Th9 cells, and is involved in various physiological processes, such as the proliferation and activation of mast cells, the enhancement of IgE production by B cells, and the promotion of inflammation. Research into IL-9 and its recombinant protein has garnered significant attention due to its potential therapeutic applications. Elevated levels of IL-9 have been associated with allergic conditions, such as asthma, and its role in driving chronic inflammation makes it a key target for intervention. Recombinant IL-9 has been investigated for its effects on immune cell behavior and its influence on airway hypersensitivity. Furthermore, understanding the mechanisms of IL-9 signaling can lead to novel strategies for treating Th2-driven diseases. The exploration of IL-9’s function provides insights that may contribute to developing monoclonal antibodies or small-molecule inhibitors, aimed at modulating immune responses and offering new treatment options for patients suffering from allergic and autoimmune disorders. As such, the study of IL-9 as a recombinant protein not only enhances our understanding of immune regulation but also opens avenues for innovative therapeutic interventions.












