Analytical Data
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基因名
IL7
- Application
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别名
IL7;Interleukin-7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13232
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表达区间
26-177aa
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氨基酸序列
DCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDAN KEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRK PAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTK EH
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分子量
17 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Interleukin-7 (IL-7) is a crucial cytokine involved in the regulation of immune responses, particularly in the development and homeostasis of T and B lymphocytes. Its importance in immunology has garnered significant attention, as it plays a vital role in lymphocyte survival, proliferation, and differentiation. Research into recombinant IL-7 protein has intensified due to its potential therapeutic applications, particularly in enhancing immune recovery in immunocompromised patients, such as those undergoing cancer treatment or individuals with HIV/AIDS. Recombinant IL-7 has been studied for its ability to restore T cell populations, improve immune function, and ultimately enhance the efficacy of vaccines and immunotherapies. Additionally, its role in promoting the development of lymphoid tissues has implications for understanding immune system maturation and function in health and disease. Given the rising urgency of addressing immunodeficient conditions, the exploration of recombinant IL-7 as a treatment modality signifies a promising frontier in immunotherapeutics and regenerative medicine, potentially leading to improved clinical outcomes in various patient populations.
