Analytical Data
-
基因名
IL17RB
- Application
-
别名
IL17RB;CRL4;EVI27;IL17BR;Interleukin-17 receptor B
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NRM6
-
表达区间
1-502aa
-
氨基酸序列
MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IL17RB, or Interleukin-17 receptor B, is a member of the IL-17 receptor family that plays a significant role in the immune response and inflammation. It is known to be involved in various biological processes, including the regulation of T-helper cell differentiation and the proliferation of certain immune cells. Research into IL17RB has gained traction due to its potential implications in various diseases, particularly those related to allergic responses, asthma, and other inflammatory conditions. The receptor's ability to interact with IL-25, an inflammatory cytokine, positions it as a crucial player in mediating type 2 immune responses. Studies have shown that IL17RB is expressed in multiple tissues, including the lungs and intestines, highlighting its relevance in organ-specific immune responses. Given its role in modulating inflammation, understanding the structure and function of IL17RB at the molecular level is critical for developing therapeutic strategies aimed at targeting inflammation-related disorders. Moreover, the use of recombinant IL17RB protein in functional assays has provided valuable insights into its signaling pathways and potential as a biomarker for certain diseases. Thus, the investigation of IL17RB and its recombinant protein forms could pave the way for novel treatment modalities that effectively manage hypersensitivity and inflammatory diseases. As researchers continue to explore its therapeutic potential, the advancements in recombinant protein technology may aid in unraveling the complexities of IL17RB mediated immune responses, ultimately contributing to better disease management and patient outcomes.
