Analytical Data
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基因名
HNRPK
- Application
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别名
HNRPK；HNRPK；Heterogeneous nuclear ribonucleoProtein K
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P61978
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表达区间
1-463aa
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氨基酸序列
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQ SKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEI LKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLL IHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPD RVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRP VGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAID TWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAG SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYL LQNSVKQYSGKFF
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分子量
77 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HNRPK (heterogeneous nuclear ribonucleoprotein K) is a multi-functional protein primarily involved in RNA processing and regulation, playing significant roles in mRNA metabolism, DNA repair, and cell signaling pathways. Its dysregulation has been implicated in various diseases, including cancer, where it contributes to tumorigenesis and metastasis by affecting gene expression and cellular responses. The study of HNRPK has gained considerable attention due to its potential as a biomarker for disease prognosis and as a target for therapeutic interventions. Researchers have focused on the characterization of its structural properties and functional domains to elucidate its mechanisms of action. Since HNRPK interacts with multiple RNA species and proteins, understanding its interaction networks is crucial for deciphering its role in cellular processes. Recent advances in proteomics and molecular biology techniques have facilitated the exploration of HNRPK’s involvement in stress responses and its impact on cellular fate decisions. By characterizing HNRPK recombinant proteins, scientists aim to develop novel strategies for targeted therapies and to enhance our understanding of RNA biology in health and disease.
