Analytical Data
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Gene name
IMP4
- Application
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Alternative Names
Brix domain containing protein 4; Brix domain-containing protein 4; BXDC4; D1Wsu40e; IMP4; IMP4; U3 small nucleolar ribonucleoprotein; homolog (yeast); IMP4_HUMAN; LRRGT00017; MGC19606
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96G21
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Expression Region
1-291aa
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AA Sequence
MLRREARLRREYLYRKAREEAQRSAQERKERLRRALEENRLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSTE
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Molecular Weight
60.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IMP4 (Invasin Membrane Protein 4) is a member of a family of proteins that play crucial roles in cellular signaling, immune response, and pathogen invasion. Research on IMP4 has gained traction due to its potential implications in various biological processes and diseases, including cancer and infectious diseases. The protein is particularly interesting because it is implicated in the modulation of cellular pathways that regulate cell growth, differentiation, and apoptosis. Studies have shown that dysregulation of IMP4 expression may contribute to tumorigenesis and metastasis, making it a potential biomarker for cancer progression. Additionally, IMP4's interaction with viral or bacterial components suggests it may also play a role in facilitating pathogen entry and manipulation of host cell machinery. Understanding the structure and function of IMP4 through recombinant protein studies can provide insights into its mechanisms and interactions, paving the way for potential therapeutic interventions. Consequently, researchers are focusing on the successful production and purification of IMP4 recombinant proteins to study their effects in both cellular models and in vivo systems, aiming to elucidate its biological functions and explore its viability as a target for drug development. This ongoing research holds promise for advancements in medical science, particularly in creating targeted therapies for diseases associated with IMP4 dysregulation.
