Analytical Data
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Gene name
CPA3
- Application
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Alternative Names
CPA3；CYP2A3；Cytochrome P450 2A6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P15088
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Expression Region
110-417aa
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AA Sequence
IPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS
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Molecular Weight
38.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The CPA3 protein, or Carboxypeptidase A3, is an important member of the carboxypeptidase family of enzymes, which play crucial roles in various physiological processes, including protein maturation, processing of bioactive peptides, and immune responses. Originally identified in mast cells, CPA3 has garnered research interest due to its involvement in allergic responses and inflammatory diseases. Its unique substrate specificity distinguishes CPA3 from other carboxypeptidases, making it a potential target for understanding the mechanisms underlying mast cell-related conditions. Recent advances in molecular biology and genetic engineering have facilitated the study of CPA3’s structure and function, leading to insights into its enzymatic activity and regulatory mechanisms. Researchers are particularly focused on understanding how CPA3 contributes to the modulation of inflammatory mediators and its implications in conditions such as asthma and other allergic disorders. Furthermore, the potential of CPA3 as a biomarker for mast cell-related diseases is being explored, offering new avenues for diagnosis and therapeutic intervention. The ongoing investigation into CPA3’s role in health and disease aims to provide a comprehensive understanding of its significance in immunology and disease pathology, ultimately informing the development of targeted therapeutic strategies.
