Cat: PA1000-1498

Recombinant Human HRSP12 Protein,His

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Analytical Data

  • Gene name

    HRSP12

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RIDA;HRSP12;2-iminobutanoate/2-iminopropanoate deaminase

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P52758

  • Expression Region

    2-137aa

  • AA Sequence

    SSLIRRVISTAKAPGAIGPYSQAVLVDRTIYISGQIGMDPSSGQLVSGGVAEEAKQALKNMGEILKAAGCDFTNVVKTTVLLADINDFNTVNEIYKQYFKSNFPARAAYQVAALPKGSRIEIEAVAIQGPLTTASL

  • Molecular Weight

    41.4kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

HRSP12 (HRSP12 protein) is a protein that plays a crucial role in the cellular response to stress and is particularly involved in the regulation of protein synthesis during stress conditions. Understanding its structure and function is important for elucidating the underlying mechanisms of cellular stress responses, which are relevant in various biological contexts, including development, aging, and disease. Recent studies have suggested that HRSP12 may be implicated in diverse cellular processes, such as apoptosis, cell proliferation, and inflammation. Its association with various diseases, including cancer and neurodegenerative disorders, highlights the necessity of investigating its molecular interactions and signaling pathways. Research into the recombinant expression of HRSP12 protein has gained momentum, as it provides a platform for detailed biochemical analysis and functional studies. This protein's recombinant form can be utilized to dissect its roles in stress granule formation, translational regulation, and overall cellular homeostasis. By employing advanced techniques in molecular biology and biochemistry, scientists aim to characterize HRSP12's properties, interactions with other proteins, and the effects of post-translational modifications. Such studies not only deepen our understanding of the protein's biological functions but may also pave the way for therapeutic innovations targeting HRSP12-related pathways in various diseases. Overall, the exploration of HRSP12 is an emerging field that holds promise for advancing our knowledge of cellular responses to stress and for the development of novel treatment strategies in health and disease contexts.

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