Analytical Data
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基因名
HOMER3
- Application
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别名
HOMER3;Homer Protein homolog 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NSC5
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表达区间
1-361aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMMSTAR EQPIFSTRAH VFQIDPATKR NWIPAGKHAL TVSYFYDATR NVYRIISIGG AKAIINSTVT PNMTFTKTSQ KFGQWADSRA NTVYGLGFAS EQHLTQFAEK FQEVKEAARL AREKSQDGGE LTSPALGLAS HQVPPSPLVS ANGPGEEKLF RSQSADAPGP TERERLKKML SEGSVGEVQW EAEFFALQDS NNKLAGALRE ANAAAAQWRQ QLEAQRAEAE RLRQRVAELE AQAASEVTPT GEKEGLGQGQ SLEQLEALVQ TKDQEIQTLK SQTGGPREAL EAAEREETQQ KVQDLETRNA ELEHQLRAME RSLEEARAER ERARAEVGRA AQLLDVSLFE LSELREGLAR LAEAAP
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分子量
43 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HOMER3 is a member of the Homer protein family, which plays a crucial role in synaptic signaling and neuronal communication. It is known for its function as a scaffold protein that interacts with various receptors, including metabotropic glutamate receptors (mGluRs) and other signaling molecules, facilitating the formation of protein complexes in the postsynaptic density. Research into HOMER3 has gained momentum due to its potential implications in neurological disorders such as autism spectrum disorders, schizophrenia, and epilepsy, where dysregulation of synaptic signaling is a common feature. The study of HOMER3 recombinant protein offers insights into its structural and functional properties, allowing researchers to elucidate its role in synaptic plasticity and neurodevelopment. Moreover, understanding the dynamics of HOMER3 interactions can provide valuable information for developing therapeutic strategies targeting synaptic dysfunctions associated with various brain diseases. As the field of neurobiology continues to investigate the complexities of neuronal communication, HOMER3 stands out as a key player worthy of detailed exploration, with recombinant protein studies serving as a foundational element for advancing our knowledge in this area.
