Analytical Data
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基因名
HNRNPK
- Application
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别名
HNRNPK;HNRPK;Heterogeneous nuclear ribonucleoProtein K
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P61978
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表达区间
1-463aa
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氨基酸序列
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQ SKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEI LKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLL IHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPD RVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRP VGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAID TWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAG SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYL LQNSVKQYSGKFF
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分子量
77 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
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Protein Description
HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K) is a multifunctional RNA-binding protein that plays a critical role in various cellular processes, including pre-mRNA splicing, mRNA transport, and translation regulation. It has garnered significant attention in recent research due to its involvement in several cancer types, where it influences gene expression and contributes to tumorigenesis. Abnormal expression levels of HNRNPK have been linked to poor prognosis in patients, highlighting its potential as a therapeutic target. The study of recombinant HNRNPK proteins allows for a deeper understanding of its structural and functional properties, enabling researchers to elucidate the mechanisms underlying its role in RNA metabolism and tumor biology. Furthermore, the production of recombinant HNRNPK facilitates the exploration of its interactions with other cellular components, paving the way for novel strategies in cancer treatment. The study of recombinant HNRNPK is thus essential for advancing our knowledge of RNA-binding proteins in gene regulation and their implications in human health and disease.
