Cat: PA2000-214DB

Recombinant Human IL20 Protein,His

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Analytical Data

  • 基因名

    IL20

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    IL20;ZCYTO10;Interleukin-20

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9NYY1

  • 表达区间

    25-176aa

  • 氨基酸序列

    LKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDT KPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLR LCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEE TE

  • 分子量

    17 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

IL-20, a member of the interleukin-10 (IL-10) family of cytokines, plays a crucial role in the regulation of immune responses and inflammation. It is primarily produced by activated macrophages and keratinocytes, and is involved in various physiological and pathological processes, including skin disorders such as psoriasis, atopic dermatitis, and inflammatory bowel diseases. The significance of IL-20 is underscored by its ability to promote keratinocyte proliferation and differentiation, as well as its involvement in the inflammatory pathways that can exacerbate chronic conditions. Given its pivotal role in mediating inflammatory responses, researchers have focused on recombinant IL-20 proteins to investigate their therapeutic potential. Developing recombinant IL-20 allows for studying its biological functions more extensively and exploring its role in disease mechanisms. Moreover, IL-20's interaction with its receptors, IL-20R1 and IL-20R2, opens avenues for targeted treatments aimed at modulating immune responses in various inflammatory diseases. Understanding the structure-function relationship of IL-20 through recombinant technology can lead to innovative strategies for developing new therapies that either inhibit its action to reduce inflammation or utilize its effects to promote wound healing. As research progresses, recombinant IL-20 is poised to play a significant role in advancing our approach to treating immune-mediated diseases and improving patient outcomes.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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