Analytical Data
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基因名
PRELID3B
- Application
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别名
PRELID3B；C20orf45；SLMO2；PRELI domain containing Protein 3B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y3B1
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表达区间
1-194aa
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氨基酸序列
MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDPSGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQDPEKTVLTQEAIITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHKLNAEIEELTASARGTIRTPMAAAAFAEK
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分子量
27.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRELID3B, a member of the prelamin A/C and lamin B receptor family, is a protein that plays a significant role in cellular processes related to lipid metabolism and membrane dynamics. Research has indicated that PRELID3B is primarily localized in the mitochondria and is involved in the regulation of mitochondrial structure and function. Recent studies have suggested that PRELID3B may participate in lipid droplet formation and mitochondrial lipid homeostasis, which are critical for energy metabolism and cellular signaling. Additionally, its expression is linked to various physiological processes, including cell differentiation and apoptosis. Abnormalities in PRELID3B expression have been associated with certain diseases, highlighting its potential as a biomarker or therapeutic target in conditions such as metabolic disorders and cancer. Given these implications, ongoing investigations seek to elucidate the precise molecular mechanisms by which PRELID3B influences cellular functions and to assess its potential role in disease progression and therapy. Overall, the study of PRELID3B presents a promising avenue for understanding the intricate relationship between mitochondrial health, lipid metabolism, and disease states.
