Cat: PA1000-1462

Recombinant Human HMGA2 Protein,His

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Analytical Data

  • 基因名

    HMGA2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    HMGA2;HMGIC;High mobility group Protein HMGI-C

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P52926

  • 表达区间

    1-109aa

  • 氨基酸序列

    MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP SKAAQKKAEA TGEKRPRGRP RKWPQQVVQK KPAQEETEET SSQESAEEDL EHHHHHH

  • 分子量

    13 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

HMGA2 (High Mobility Group A2) is a non-histone chromosomal protein that plays a crucial role in gene expression regulation, cell proliferation, and differentiation. It has been implicated in various biological processes, including embryonic development and tumorigenesis. The study of HMGA2 is particularly important due to its association with several types of cancers, where its overexpression can contribute to malignant transformation and increased metastatic potential. Researchers have been focusing on the recombinant expression of HMGA2 to better understand its structure-function relationship and its interactions with DNA and other proteins. By producing HMGA2 as a recombinant protein, scientists can investigate its binding affinities, cellular localization, and regulatory mechanisms in a controlled environment. This research has the potential to uncover novel therapeutic targets and strategies for cancer treatment, as well as provide insights into the molecular pathways regulated by HMGA2 in normal and pathological conditions. Furthermore, studying HMGA2's role in developmental biology could lead to advances in regenerative medicine and tissue engineering. Overall, the investigation of HMGA2 recombinant proteins forms a vital part of ongoing research aimed at deciphering the complex roles of this protein in health and disease.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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