Analytical Data
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基因名
IFRG15
- Application
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别名
TOR1AIP2; IFRG15; LULL1; Torsin-1A-interacting protein 2; Lumenal domain-like LAP1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NFQ8
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表达区间
1-131aa
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氨基酸序列
MFSDNSHCPDCGQQWFPSLELGHWLYQTELVENECYQVFLDRINRADYCPECYPDNPANRSLVLPWSFPLEWAPQNLTRWTFEKACHPFLLGPPLVRKRIHDSRVAGFNPALQLILTRTDKTLNKKLGQNK
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分子量
41.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IFRG15, also known as Interferon Regulated Gene 15, is a member of the ISG15 family, which plays a crucial role in the immune response, particularly in the context of viral infections and inflammation. This protein functions as a ubiquitin-like modifier, facilitating the post-translational modification of target proteins through a process known as ISGylation. This modification can influence various cellular processes, including protein stability, localization, and activity, thereby affecting the overall immune response. Research on IFRG15 has gained significant attention due to its potential implications in various diseases, including cancer and autoimmune disorders. Studies have demonstrated that IFRG15 expression can be induced by type I interferons, linking it to antiviral defense mechanisms. Additionally, aberrant regulation of IFRG15 has been associated with pathological conditions, making it a promising target for therapeutic interventions. Understanding the structure and function of IFRG15 through recombinant protein studies can provide insights into its role in immune modulation, paving the way for novel strategies in disease management and treatment.
