Cat: PA1000-1452

Recombinant Human HIV1-p24 Protein,His

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Analytical Data

  • Gene name

    HIV1-p24

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ;

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P12497

  • Expression Region

    133-363aa

  • AA Sequence

    PIVQNLQG QMVHQAISPR TLNAWVKVVE EKAFSPEVIP MFSALSEGAT PQDLNTMLNT VGGHQAAMQM LKETINEEAA EWDRLHPVHA GPIAPGQMRE PRGSDIAGTT STLQEQIGWM THNPPIPVGE IYKRWIILGL NKIVRMYSPT SILDIRQGPK EPFRDYVDRF YKTLRAEQAS QEVKNWMTET LLVQNANPDC KTILKALGPG ATLEEMMTAC QGVGGPGHKA RVL

  • Molecular Weight

    24 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

HIV-1 p24 recombinant protein is a crucial component in the study of Human Immunodeficiency Virus (HIV), particularly in understanding its structure and function. The p24 protein is a core structural protein of the HIV-1 virus, playing an essential role in the formation and stability of the viral core. Research on p24 is vital because it is a principal target for both the immune response in infected individuals and the development of therapeutics and diagnostics. The study of this recombinant protein has paved the way for advancements in vaccine development, as it can elicit potent immune responses. Additionally, p24 is commonly used in assays to monitor viral load in HIV-infected patients, making it an invaluable biomarker in clinical settings. Given the global impact of HIV/AIDS, understanding the properties and behavior of the p24 protein can contribute significantly to the development of effective antiviral strategies and improve the overall management of the disease. Consequently, ongoing research focuses on characterizing the immunogenicity of p24, investigating its potential as a vaccine candidate, and exploring novel therapeutic approaches that target this viral protein.

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