Cat: PA2000-8411

Recombinant Human IFI44L Protein,GST

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Analytical Data

  • Gene name

    IFI44L

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    IFI44L; C1orf29; GS3686Interferon-induced protein 44-like

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q53G44

  • Expression Region

    1-452aa

  • AA Sequence

    MEVTTRLTWN DENHLRKLLG NVSLSLLYKS SVHGGSIEDM VERCSRQGCT ITMAYIDYNM IVAFMLGNYI NLHESSTEPN DSLWFSLQKK NDTTEIETLL LNTAPKIIDE QLVCRLSKTD IFIICRDNKI YLDKMITRNL KLRFYGHRQY LECEVFRVEG IKDNLDDIKR IIKAREHRNR LLADIRDYRP YADLVSEIRI LLVGPVGSGK SSFFNSVKSI FHGHVTGQAV VGSDITSITE RYRIYSVKDG KNGKSLPFML CDTMGLDGAE GAGLCMDDIP HILKGCMPDR YQFNSRKPIT PEHSTFITSP SLKDRIHCVA YVLDINSIDN LYSKMLAKVK QVHKEVLNCG IAYVALLTKV DDCSEVLQDN FLNMSRSMTS QSRVMNVHKM LGIPISNILM VGNYASDLEL DPMKDILILS ALRQMLRAAD DFLEDLPLEE TGAIERALQP CI

  • Molecular Weight

    51.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

IFI44L (Interferon-Inducible Protein 44 Like) is a member of the interferon-stimulated gene family and plays a pivotal role in the immune response, particularly in antiviral defense mechanisms. Its expression is highly regulated and induced by type I interferons, which are secreted in response to viral infections. Research has indicated that IFI44L may influence various cellular processes, including apoptosis, cell proliferation, and the modulation of immune signaling pathways. In recent years, studies have focused on its potential role in chronic viral infections, autoimmune diseases, and cancer, highlighting the protein's significance in both innate and adaptive immunity. Investigating the structure and function of recombinant IFI44L is crucial for understanding its biological activities and therapeutic potential. The recombinant protein has been used in various assays to elucidate its interactions with other cellular proteins, its effect on viral replication, and its influence on immune cell responses. Understanding the molecular mechanisms by which IFI44L exerts its effects could provide insights into developing novel therapeutic strategies for treating viral infections and immune-related disorders. This research area continues to evolve, revealing the multifaceted role of IFI44L in health and disease.

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