Analytical Data
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Gene name
HINT2
- Application
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Alternative Names
HINT2;Adenosine 5'-monophosphoramidase HINT2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BX68
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Expression Region
18-163aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSVAATGVR GGQVRGAAGV TDGNEVAKAQ QATPGGAAPT IFSRILDKSL PADILYEDQQ CLVFRDVAPQ APVHFLVIPK KPIPRISQAE EEDQQLLGHL LLVAKQTAKA EGLGDGYRLV INDGKLGAQS VYHLHIHVLG GRQLQWPPG
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Molecular Weight
18 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HINT2 (histidine triad nucleotide-binding protein 2) is an intriguing member of the histidine triad (HIT) family, which is known for its role in various cellular processes, including nucleotide binding and hydrolysis. Research on HINT2 has gained attention due to its involvement in critical biological functions such as cellular signaling, proliferation, and apoptosis. Notably, HINT2 is implicated in the regulation of cellular responses to stress, making it a potential player in neurodegenerative diseases and various types of cancer. Investigations into HINT2 have revealed its potential as a therapeutic target, as alterations in its expression and function can contribute to disease progression. Moreover, HINT2's ability to interact with other proteins underscores its complex role in intricate cellular networks. Understanding the structural and functional properties of HINT2 is essential for elucidating its biological significance and therapeutic potential. Recent studies utilizing recombinant protein technology have enabled the production and characterization of HINT2, facilitating advancements in our comprehension of its mechanism of action. This research is pivotal for exploring HINT2's role in health and disease, potentially leading to the development of novel strategies for intervention in respiratory diseases, metabolic disorders, and other conditions where HINT2's function may be disrupted. As studies continue to elucidate the multifaceted roles of HINT2, its recombinant protein will serve as a vital tool for further investigations into its biological pathways and interactions within the cellular milieu.
