Analytical Data
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基因名
IER5
- Application
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别名
IER5; PP4583; SBBI48; Immediate early response gene 5 protein
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5VY09
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表达区间
1-327aa
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氨基酸序列
MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPRPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRDMNPWSTAIVAF
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分子量
60.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IER5 (Immediate Early Response 5) is a protein that has garnered attention in recent years due to its role in cellular responses to stress and its involvement in various physiological processes. Originally identified as an immediate early gene, IER5 is rapidly expressed in response to signaling pathways such as those activated by growth factors and stressors, suggesting a critical function in cellular adaptation and survival. Research has indicated that IER5 may play a significant role in regulating cell proliferation, differentiation, and apoptosis, making it a potential target for therapeutic interventions in diseases like cancer and neurodegenerative disorders. Additionally, the study of IER5 in the context of developmental biology has uncovered its importance in embryonic development and tissue homeostasis. As a result, the recombinant expression of IER5 protein has become a focal point for researchers aiming to elucidate its biochemical properties, interaction networks, and mechanisms of action. Through the production of recombinant IER5, scientists seek to gain insights into its functional roles, which may lead to novel approaches for disease treatment and understanding the underlying mechanisms of cellular stress responses. The ongoing exploration of IER5 stands at the intersection of molecular biology, biochemistry, and translational medicine, highlighting its potential as a valuable biomarker and therapeutic target.
