Analytical Data
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Gene name
IER5
- Application
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Alternative Names
IER5; PP4583; SBBI48; Immediate early response gene 5 protein
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5VY09
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Expression Region
1-327aa
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AA Sequence
MEFKLEAHRIVSISLGKIYNSRVQRGGIKLHKNLLVSLVLRSARQVYLSDPCPGLYLAGPAGTPAPPPQQQPGEPAAGPPAGWGEPPPPAARASWPETEPQPERSSVSDAPRVGDEVPVATVTGVGDVFQGGEADATEAAWSRVEGPRQAAAREAEGTAGGWGVFPEVSRAARRPCGCPLGGEDPPGTPAATPRAACCCAPRPAEDEPPAPPAVCPRKRCAAGVGGGPAGCPAPGSTPLKKPRRNLEQPPSGGEDDDAEEMETGNVANLISIFGSSFSGLLRKSPGGGREEEEGEESGPEAAEPGQICCDKPVLRDMNPWSTAIVAF
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Molecular Weight
60.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IER5 (Immediate Early Response 5) is a protein that has garnered attention in recent years due to its role in cellular responses to stress and its involvement in various physiological processes. Originally identified as an immediate early gene, IER5 is rapidly expressed in response to signaling pathways such as those activated by growth factors and stressors, suggesting a critical function in cellular adaptation and survival. Research has indicated that IER5 may play a significant role in regulating cell proliferation, differentiation, and apoptosis, making it a potential target for therapeutic interventions in diseases like cancer and neurodegenerative disorders. Additionally, the study of IER5 in the context of developmental biology has uncovered its importance in embryonic development and tissue homeostasis. As a result, the recombinant expression of IER5 protein has become a focal point for researchers aiming to elucidate its biochemical properties, interaction networks, and mechanisms of action. Through the production of recombinant IER5, scientists seek to gain insights into its functional roles, which may lead to novel approaches for disease treatment and understanding the underlying mechanisms of cellular stress responses. The ongoing exploration of IER5 stands at the intersection of molecular biology, biochemistry, and translational medicine, highlighting its potential as a valuable biomarker and therapeutic target.
