Cat: PA1000-1432

Recombinant Human HES7 Protein,His

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Analytical Data

  • 基因名

    HES7

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    HES7;BHLHB37;Transcription factor HES-7

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9BYE0

  • 表达区间

    1-225aa

  • 氨基酸序列

    MVTRDRAENR DGPKMLKPLV EKRRRDRINR SLEELRLLLL ERTRDQNLRN PKLEKAEILE FAVGYLRERS RVEPPGVPRS PVQDAEALAS CYLSGFRECL LRLAAFAHDA SPAARAQLFS ALHGYLRPKP PRPKPVDPRP PAPRPSLDPA APALGPALHQ RPPVHQGHPS PRCAWSPSLC SPRAGDSGAP APLTGLLPPP PPPHRQDGAP KAPLPPPPAF WRPWP

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

HES7, a member of the Hairy/Enhancer of Split (HES) family of transcription factors, plays a critical role in the development and differentiation of various cell types, particularly in the context of the Notch signaling pathway. This pathway is essential for regulating gene expression during embryogenesis and tissue homeostasis. Research into HES7 has gained traction due to its implications in developmental biology and its potential association with various diseases, including certain cancers and developmental disorders. The study of HES7 recombinant proteins is pivotal for understanding the molecular mechanisms by which HES7 influences cell fate decisions and interacts with other transcription factors and signaling pathways. Through the expression and purification of HES7 recombinant proteins, researchers aim to elucidate its functional dynamics, including DNA-binding properties and protein-protein interactions. This knowledge is crucial for assessing how HES7 contributes to cellular processes such as proliferation, apoptosis, and differentiation. Furthermore, understanding HES7's role at a molecular level could uncover new therapeutic targets for diseases linked to aberrant HES7 activity. As such, the research surrounding HES7 recombinant proteins holds significant promise for advancing our understanding of both normal developmental processes and pathological conditions, potentially leading to innovative strategies in regenerative medicine and targeted therapies.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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