Analytical Data
-
Gene name
HDHD3
- Application
-
Alternative Names
HDHD3;C9orf158;Haloacid dehalogenase-like hydrolase domain-containing Protein 3
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9BSH5
-
Expression Region
1-251aa
-
AA Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAHR LQIRLLTWDV KDTLLRLRHP LGEAYATKAR AHGLEVEPSA LEQGFRQAYR AQSHSFPNYG LSHGLTSRQW WLDVVLQTFH LAGVQDAQAV APIAEQLYKD FSHPCTWQVL DGAEDTLREC RTRGLRLAVI SNFDRRLEGI LEGLGLREHF DFVLTSEAAG WPKPDPRIFQ EALRLAHMEP VVAAHVGDNY LCDYQGPRAV GMHSFLVVGP QALDPVVRDS VPKEHILPSL AHLLPALDCL EGSTPGL
-
Molecular Weight
32 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HDHD3, a member of the haloacid dehalogenase (HAD) superfamily, has garnered significant attention in recent years due to its role in various biochemical processes. This enzyme plays a crucial part in phosphate metabolism and is involved in catalyzing the hydrolysis of phosphate esters and anhydrides, which are essential reactions in cellular signaling and energy transfer. The study of HDHD3 is particularly relevant in the context of human diseases, including cancer and neurodegenerative disorders, where dysregulation of phosphate metabolism has been implicated. Understanding the structural and functional characteristics of HDHD3 can provide insights into its enzymatic mechanism, enabling the development of therapeutic strategies aimed at modulating its activity. Additionally, advancements in recombinant DNA technology have facilitated the production of HDHD3 as a recombinant protein, allowing for detailed biophysical and biochemical analyses. Research on HDHD3 may also uncover potential biomarkers for disease progression and facilitate the design of small molecule inhibitors or activators, thereby broadening the scope of therapeutic interventions. As a result, investigating the HDHD3 recombinant protein holds promise not only for enhancing our understanding of fundamental biological processes but also for translating this knowledge into practical applications in medicine and biotechnology.
