Analytical Data
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Gene name
HOXB5
- Application
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Alternative Names
HGNC:5116; HHO.C10; Homeo box 2A; Homeo box B5; Homeobox 2A; Homeobox B5; Homeobox protein HHO.C10; Homeobox protein Hox B5; Homeobox protein Hox-2A; Homeobox protein Hox-B5; Homeobox protein HoxB5; Homeobox protein Hu-1; Homeobox2A; HomeoboxB5; HOX 2; Hox 2.1; HOX 2A; HOX B5; HOX2; Hox2.1; Hox2.1. mouse. homolog of; HOX2A; HOXB 5; Hoxb5; HU 1; HU1; HXB5_HUMAN
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P09067
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Expression Region
1-269aa
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AA Sequence
MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP
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Molecular Weight
55.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HoxB5 is a member of the homeobox gene family, which plays a crucial role in the regulation of developmental processes and cell differentiation. It is particularly significant in the development of the respiratory system and has been implicated in various biological processes, including cell proliferation, apoptosis, and stem cell maintenance. Research has shown that HoxB5 expression is tightly regulated during embryogenesis and in adult tissues, influencing the fate of progenitor cells and their differentiation paths. Moreover, HoxB5 has been linked to certain cancers, making it a potential biomarker and therapeutic target. The recombinant protein of HoxB5 enables researchers to study its functional properties, interactions with other proteins, and its role in developmental and disease contexts. Its availability allows for in vitro and in vivo experiments to elucidate the mechanisms underlying HoxB5 signaling pathways and their contributions to cellular behaviors. Understanding these pathways is essential for developing targeted therapies, particularly in oncology and regenerative medicine. Consequently, the study of HoxB5 recombinant protein not only enhances our comprehension of fundamental biological processes but also opens up avenues for innovative therapeutic strategies.
