Analytical Data
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基因名
ERVK-5
- Application
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别名
ERVK-5；ERVK5；Endogenous retrovirus group K member 5 Gag polyProtein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9HDB9
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表达区间
2-667aa
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氨基酸序列
GQTKSKTKSKYASYLSFIKILLKRGGVRVSTKNLIKLFQIIEQFCPWFPEQGTLDLKDWKRIGEELKQAGRKGNIIPLTVWNDWAIIKAALEPFQTKEDSVSVSDAPGSCVIDCNEKTGRKSQKETESLHCEYVTEPVMAQSTQNVDYNQLQGVIYPETLKLEGKGPELVGPSESKPRGPSPLPAGQVPVTLQPQTQVKENKTQPPVAYQYWPPAELQYLPPPESQYGYPGMPPALQGRAPYPQPPTVRLNPTASRSGQGGTLHAVIDEARKQGDLEAWRFLVILQLVQAGEETQVGAPARAETRCEPFTMKMLKDIKEGVKQYGSNSPYIRTLLDSIAHGNRLTPYDWESLAKSSLSSSQYLQFKTWWIDGVQEQVRKNQATKPTVNIDADQLLGTGPNWSTINQQSVMQNEAIEQVRAICLRAWGKIQDPGTAFPINSIRQGSKEPYPDFVARLQDAAQKSITDDNARKVIVELMAYENANPECQSAIKPLKGKVPAGVDVITEYVKACDGIGGAMHKAMLMAQAMRGLTLGGQVRTFGKKCYNCGQIGHLKRSCPVLNKQNIINQAITAKNKKPSGLCPKCGKGKHWANQCHSKFDKDGQPLSGNRKRGQPQAPQQTGAFPVQLFVPQGFQGQQPLQKIPPLQGVSQLQQSNSCPAPQQAAPQ
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分子量
80.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ERVK-5, a member of the endogenous retrovirus family, has garnered attention in recent years due to its potential roles in health and disease. Endogenous retroviruses, such as ERVK-5, are remnants of ancient viral infections that have become integrated into the human genome over millions of years. ERVK-5 is particularly noteworthy as it has been implicated in several biological processes, including immunoregulation, gene expression modulation, and possible involvement in various diseases, such as cancer and autoimmune disorders. Research suggests that ERVK-5 may influence the expression of nearby genes and contribute to the regulation of immune responses, making it a potential biomarker for certain conditions. Additionally, the presentation of ERVK-5-derived peptides could impact T-cell responses, adding another layer of complexity to its functional roles. Understanding the mechanisms by which ERVK-5 and its encoded proteins operate can provide valuable insights into their contributions to human health and disease pathogenesis. Consequently, ongoing studies focus on elucidating the molecular functions of the ERVK-5 recombinant protein, exploring its potential applications in diagnostics and therapeutics, and assessing its relevance in the context of viral infections and tumor immunity. This research is critical for developing new strategies to harness the beneficial aspects of endogenous retroviruses while mitigating their potential pathogenic effects.
