Analytical Data
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基因名
BZLF2
- Application
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别名
BZLF2；HLA-DRA1；HLA class II histocompatibility antigen. DR alpha chain
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种属
E.coli
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P0C6Z5
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表达区间
34-223aa
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氨基酸序列
GGRVAAAAITWVPKPNVEVWPVDPPPPVNFNKTAEQEYGDKEVKLPHWTPTLHTFQVPQNYTKANCTYCNTREYTFSYKGCCFYFTKKKHTWNGCFQACAELYPCTYFYGPTPDILPVVTRNLNAIESLWVGVYRVGEGNWTSLDGGTFKVYQIFGSHCTYVSKFSTVPVSHHECSFLKPCLCVSQRSNS
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分子量
25.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BZLF2, also known as ZEBRA, is a key regulatory protein encoded by the Epstein-Barr Virus (EBV), a member of the herpesvirus family. EBV is notorious for its association with several human diseases, including infectious mononucleosis and various malignancies such as Burkitt's lymphoma and nasopharyngeal carcinoma. BZLF2 plays a pivotal role in the lytic cycle of EBV, acting as a transcription factor that activates the expression of viral genes necessary for viral replication and cell lysis. Research on BZLF2 is crucial for understanding the molecular mechanisms underlying EBV pathogenesis and for developing potential therapeutic strategies. Recombinant BZLF2 protein studies enable the investigation of its functional properties, interactions with cellular proteins, and its role in modulating the host immune response. Moreover, elucidating the structural characteristics of BZLF2 can provide insights into its binding mechanisms and influence on host cellular pathways. As such, the recombinant production of BZLF2 is a significant area of study, contributing to our broader understanding of herpesvirus biology and the development of antiviral therapies targeting EBV-related diseases.
