Analytical Data
-
基因名
GNPDA1
- Application
-
别名
GNPDA1;GNPI;HLN;KIAA0060;Glucosamine-6-phosphate isomerase 1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P46926
-
表达区间
1-289aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MKLIILEHYS QASEWAAKYI RNRIIQFNPG PEKYFTLGLP TGSTPLGCYK KLIEYYKNGD LSFKYVKTFN MDEYVGLPRD HPESYHSFMW NNFFKHIDIH PENTHILDGN AVDLQAECDA FEEKIKAAGG IELFVGGIGP DGHIAFNEPG SSLVSRTRVK TLAMDTILAN ARFFDGELTK VPTMALTVGV GTVMDAREVM ILITGAHKAF ALYKAIEEGV NHMWTVSAFQ QHPRTVFVCD EDATLELKVK TVKYFKGLML VHNKLVDPLY SIKEKETEKS QSSKKPYSD
-
分子量
35 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GNPDA1 (Glucosamine-6-phosphate isomerase 1) has garnered significant attention in recent years due to its pivotal role in cellular metabolism and potential implications in various diseases. This enzyme catalyzes the isomerization of glucosamine-6-phosphate, playing a crucial part in the hexosamine biosynthetic pathway, which is linked to cellular signaling, growth, and stress responses. Dysregulation of this pathway has been associated with metabolic disorders, including obesity and diabetes, as well as neurodegenerative diseases like Alzheimer's. Emerging research indicates that GNPDA1 may also influence the development of certain cancers, making it a promising target for therapeutic intervention. The recombinant expression of GNPDA1 allows for a deeper understanding of its functional mechanisms and provides a valuable tool for drug discovery. By studying the enzyme's structure and activity, researchers aim to identify inhibitors that can modulate its function in disease contexts. Furthermore, insights from such studies could pave the way for novel strategies in metabolic disease management and cancer therapy. Overall, the investigation of GNPDA1 not only enhances our comprehension of metabolic processes but also holds considerable potential for advancing medical science.
