Analytical Data
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Gene name
CK16
- Application
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Alternative Names
CK16;C11orf56;FAM160A2;KIAA1759;FHF complex subunit HOOK-interacting Protein 1B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P08779
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Expression Region
1-473aa
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AA Sequence
MTTCSRQFTS SSSMKGSCGI GGGIGGGSSR ISSVLAGGSC RAPSTYGGGL SVSSRFSSGG ACGLGGGYGG GFSSSSSFGS GFGGGYGGGL GAGFGGGLGA GFGGGFAGGD GLLVGSEKVT MQNLNDRLAS YLDKVRALEE ANADLEVKIR DWYQRQRPSE IKDYSPYFKT IEDLRNKIIA ATIENAQPIL QIDNARLAAD DFRTKYEHEL ALRQTVEADV NGLRRVLDEL TLARTDLEMQ IEGLKEELAY LRKNHEEEML ALRGQTGGDV NVEMDAAPGV DLSRILNEMR DQYEQMAEKN RRDAETWFLS KTEELNKEVA SNSELVQSSR SEVTELRRVL QGLEIELQSQ LSMKASLENS LEETKGRYCM QLSQIQGLIG SVEEQLAQLR CEMEQQSQEY QILLDVKTRL EQEIATYRRL LEGEDAHLSS QQASGQSYSS REVFTSSSSS SSRQTRPILK EQSSSSFSQG QSS
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Molecular Weight
51.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CK16 recombinant protein, derived from the cytokeratin 16 gene, plays a significant role in various biological processes, particularly in maintaining the structural integrity of epithelial tissues. Its expression is predominantly observed in stratified squamous epithelia, such as in the skin and mucosal surfaces, where it contributes to the formation and function of the keratinocyte layer. Pathologically, CK16 is upregulated in response to skin injuries, inflammatory conditions, and certain diseases, such as psoriasis and other hyperproliferative disorders. Researchers have identified CK16 as a potential biomarker for these conditions, enhancing its relevance in clinical diagnostics and therapeutic strategies. The production of CK16 recombinant protein allows for detailed studies of its structural and functional properties, facilitating insights into its role in keratinocyte biology and tissue repair mechanisms. Furthermore, the recombinant form can be utilized in various applications, including the development of skin substitutes and regenerative medicine. Understanding CK16's functional implications can provide avenues for novel treatments targeting epithelial disorders, making it a focus of ongoing biomedical research.











