Analytical Data
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Gene name
GTPBP3
- Application
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Alternative Names
GTPBP3; MTGP1; tRNA modification GTPase GTPBP3; mitochondrial; GTP-binding protein 3; Mitochondrial GTP-binding protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q969Y2
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Expression Region
1-492aa
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AA Sequence
MWRGLWTLAAQAARGPRRLCTRRSSGAPAPGSGATIFALSSGQGRCGIAVIRTSGPASGHALRILTAPRDLPLARHASLRLLSDPRSGEPLDRALVLWFPGPQSFTGEDCVEFHVHGGPAVVSGVLQALGSVPGLRPAEAGEFTRRAFANGKLNLTEVEGLADLIHAETEAQRRQALRQLDGELGHLCRGWAETLTKALAHVEAYIDFGEDDNLEEGVLEQADIEVRALQVALGAHLRDARRGQRLRSGAHVVVTGPPNAGKSSLVNLLSRKPVSIVSPEPGTTRDVLETPVDLAGFPVLLSDTAGLREGVGPVEQEGVRRARERLEQADLILAMLDASDLASPSSCNFLATVVASVGAQSPSDSSQRLLLVLNKSDLLSPEGPGPGPDLPPHLLLSCLTGEGLDGLLEALRKELAAVCGDPSTDPPLLTRARHQHHLQGCLDALGHYKQSKDLALAAEALRVARGHLTRLTGGGGTEEILDIIFQDFCVGK
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Molecular Weight
78.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GTPBP3, or GTP-binding protein 3, is a member of the GTPase family, which plays a crucial role in various cellular processes, including protein synthesis, signal transduction, and cell cycle regulation. Research into GTPBP3 has gained momentum due to its potential implications in human health and disease. Specifically, it has been implicated in mitochondrial function, with studies suggesting that it may influence mitochondrial RNA metabolism and translation. Dysregulation of GTPBP3 has also been associated with several pathologies, including certain cancers and neurodegenerative diseases. The recombinant expression of GTPBP3 provides a valuable tool for elucidating its biological functions and mechanisms, enabling researchers to investigate its interactions with other proteins and its role in cellular pathways. Understanding the structure and function of GTPBP3 at the molecular level may pave the way for identifying therapeutic targets, potentially leading to the development of novel strategies for disease intervention. Overall, the study of GTPBP3 and its recombinant forms offers significant insights into fundamental cellular processes and their implications in health and disease.
