Analytical Data
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Gene name
TJP1
- Application
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Alternative Names
TJP1；ZO1；Tight junction Protein ZO-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q07157
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TJP1, also known as tight junction protein 1 or ZO-1, is a crucial protein in the formation and maintenance of tight junctions between epithelial and endothelial cells. These tight junctions are essential for regulating paracellular permeability and maintaining the integrity of cellular barriers in tissues. Research into TJP1 has gained significant attention due to its role in various physiological and pathological processes, including cell signaling, cell migration, and disease progression. Dysregulation of TJP1 has been implicated in several conditions, such as cancer, inflammatory diseases, and neurological disorders, emphasizing its importance in cellular homeostasis. The study of recombinant TJP1 protein offers valuable insights into its structural and functional properties, enabling researchers to explore the mechanisms underlying tight junction assembly and disassembly. Additionally, recombinant TJP1 can serve as a potential therapeutic target or biomarker for related diseases, providing avenues for developing novel treatment strategies. Understanding the precise functions and interactions of TJP1 at the molecular level is crucial for elucidating its contributions to health and disease, making it a focal point of research in cell biology and medical science.
