Analytical Data
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基因名
GART
- Application
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别名
GART；PGFT；PRGS；Trifunctional purine biosynthetic Protein adenosine-3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P22102
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表达区间
111–318aa
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氨基酸序列
KEFMDRHGIPTAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAFGAAGETIVIEELLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAPQVSNDLLLKIKDTVLQRTVDGMQQEGTPYTGILYAGIMLTKNGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTLD
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分子量
26.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GART (generating amino acid-rich transmembrane) is a pivotal protein involved in several biological processes, including nucleotide synthesis and cellular stress response. Its multifaceted roles make it an attractive target for researchers focusing on metabolic disorders and cancer. The GART protein is part of the purine biosynthesis pathway, facilitating the conversion of amino acids into critical nucleotide precursors. Dysregulation of this pathway is often linked to various diseases, including certain types of cancer. Recent advances in protein engineering and structural biology have provided insights into GART's conformational dynamics and interactions with other cellular components. As a result, researchers are exploring GART as a potential biomarker for disease progression and as a target for therapeutic interventions. Additionally, the development of GART-derived recombinant proteins may allow for the creation of novel treatments that enhance the efficacy of existing therapies. The ongoing investigation into GART's structure-function relationships aims to unravel the complexities of its biological activities and improve our understanding of its role in health and disease. With the rising incidence of metabolic disorders and cancer, GART research holds significant promise for contributing to innovative diagnostic and therapeutic strategies.
